When it comes to skin rejuvenation treatments, the debate between Rejuran S and Standard Rejuran often comes up. Both use polynucleotides (PN) derived from salmon DNA to stimulate collagen production, but the differences lie in their formulation and real-world performance. Let’s break down why professionals and patients are increasingly leaning toward rejuran s for targeted anti-aging solutions.
First, the concentration of active ingredients sets them apart. Rejuran S contains 20 mg/mL of highly purified polynucleotides, nearly double the 10 mg/mL found in Standard Rejuran. This isn’t just a marketing claim—clinical trials in South Korea showed a 38% improvement in skin elasticity with Rejuran S after three sessions, compared to 22% with the standard version. Higher PN density means faster neocollagenesis, which explains why clinics like Seoul’s VIP Dermatology report 90% patient satisfaction rates when using Rejuran S for deep wrinkles or acne scars.
But what does this mean for treatment timelines? With Standard Rejuran, patients typically need 4-6 sessions spaced three weeks apart to see visible results. Rejuran S cuts that to 3-4 sessions due to its optimized delivery system. Take the case of a 45-year-old Singaporean executive who tried both: “With Standard Rejuran, I waited eight weeks before noticing smoother texture. Rejuran S showed changes in just four weeks—my marionette lines softened by 60% after two treatments.” This efficiency aligns with data from Malaysia’s MJs Medicals, where 78% of clients choosing Rejuran S complete their regimen within 10 weeks versus 14 weeks for the standard option.
Cost-effectiveness often comes up in consultations. At first glance, Standard Rejuran seems cheaper at $300-$400 per vial versus $450-$550 for Rejuran S. But when you factor in fewer sessions and longer-lasting results (12-18 months for S vs. 6-9 months for standard), the math shifts. Aesthetic chain Wellaholic reported clients spent 15% less annually on maintenance with Rejuran S. As Dr. Lim from KL Aesthetic Clinic explains, “The 1.5μm particle size in Rejuran S allows deeper dermal penetration, meaning we use 30% less product per treatment area compared to the standard formula.”
Safety profiles also differ. Both have FDA Korea clearance, but Rejuran S’s advanced filtration process reduces allergy risks from 2.1% to 0.3% according to 2023 manufacturer data. This became crucial after Thailand’s 2022 regulatory update banned several PN products containing impurities—Rejuran S passed all purity tests with <0.01% protein residues. For sensitive skin types, this makes it a safer bet, especially when treating delicate zones like under-eyes where 92% of practitioners now prefer Rejuran S.Real-world applications highlight their specialized roles. Standard Rejuran still shines for mild texture issues—think early-stage forehead lines or general hydration boosts. But for complex cases like post-acne scarring or UV-damaged skin, Rejuran S delivers 2.3x better collagen density based on ultrasound imaging studies. Aesthetic centers in Hong Kong even combine both: using Standard Rejuran for broad-area treatment and Rejuran S for precision work, achieving 40% faster recovery times than single-product protocols.So which should you choose? If you’re targeting specific aged areas with higher budget flexibility, Rejuran S’s enhanced benefits justify the investment. For general maintenance on younger skin, Standard Rejuran remains practical. Either way, consult a certified provider—improper injection depth can waste 20-50% of the product’s potential regardless of formula quality. As the industry evolves, one thing’s clear: polynucleotide treatments aren’t one-size-fits-all, and understanding these nuances leads to smarter skincare investments.